** Shares of drugmaker Unity Biotechnology UBX.O down 40%
at $2.49
** UBX says its drug UBX1325 did not meet main goal of
showing "non-inferior gains" in vision clarity vs Regeneron
Pharmaceuticals' REGN.O drug Eylea
** Unity was testing the drug in a mid-stage study in
patients with wet age-related macular degeneration (wAMD) who
were not achieving maximum treatment benefits with ongoing
anti-VEGF therapy
** Anti-VEGF therapies help reduce new blood vessel growth
and are used for the treatment of wAMD, a type of disorder in
which new abnormal blood vessels develop under the retina
** Company is also studying the drug as a treatment for
macular edema, the most common cause of vision loss in diabetic
patients
** As of last close, UBX up ~51% so far this year
(Reporting by Bhanvi Satija in Bengaluru)
((Bhanvi.Satija@thomsonreuters.com; Outside U.S. +91
9873062788))