** U.S. healthcare startup Upstream Bio's UPB.O shares
rise ~26.47% above their initial public offering price in co's
market debut
** UPB last up ~23.5% at $21; stock opened for trading at
$21.50 vs IPO price of $17
** UPB, in a sign of strong investor demand, priced its
upsized IPO at higher end of its marketed range of $15 to $17
** With the shares' rise at debut, UPB now valued aT $1.05
bln
** Co raised $255 mln by selling 15 mln shares priced at $17
apiece
** J.P. Morgan, TD Cowen, Piper Sandler and William Blair
were the underwriters for the IPO
(Reporting by Prakhar Srivastava in Bengaluru)
((Prakhar.srivastava2@thomsonreuters.com))