(Updates)
** U.S.-listed shares VRNA.O of biopharma company Verona
Pharma Plc up 34.8% at $18.20, hit more than 4-1/2 year high
** Company says its experimental lung disease therapy
ensifentrine to treat COPD meets main goal in late-stage study,
with statistically significant improvements in lung function
** COPD, or chronic obstructive pulmonary disease, causes
airflow blockage and breathing-related problems
** Brokerage BTIG says ensifentrine looks approvable
** Trial showed 36% reduction in COPD exacerbations that
cause irreversible lung damage, nearly twice the reductions seen
for the currently available drug roflumilast - brokerage
** Brokerage Piper Sandler says data consistent with that
reported from an earlier trial; says two positive datasets
boosts probability of success for approval
** Marketing application planned for first half of 2023,
company says
** Including session's gain, Verona's U.S.-listed shares
have more than doubled YTD
(Reporting by Pratik Jain and Sriparna Roy in Bengaluru)
((Pratik.Jain@thomsonreuters.com))