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VRTX Vertex Pharmaceuticals News Story

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Wall Street's main indexes fell on Tuesday after U.S. President Donald Trump's latest plans for pharma tariffs renewed worries of the impact of a trade war, while some downbeat corporate results also weighed on investor sentiment. .N

At  11:30 EDT, the Dow Jones Industrial Average .DJI was down 0.34% at 41,079.37.The S&P 500 .SPX was down 0.29% at 5,634.17, and the Nasdaq Composite .IXIC was down 0.43% at 17,768.27.

The top three S&P 500 .PG.INX percentage gainers:

** Constellation Energy Corp CEG.OQ, up 10.0%

** Leidos Holdings Inc LDOS.N, up 4.6%

** Ford Motor Co F.N, up 3.8%

The top three S&P 500 .PL.INX percentage losers:

** Palantir Technologies Inc PLTR.OQ, down 12.0%

** Vertex Pharmaceuticals Inc VRTX.OQ, down 11.3%

** Coterra Energy Inc CTRA.N, down 8.1%

The top three NYSE .PG.N percentage gainers:

** Ameresco Inc AMRC.N, up 18.5%

** Regal Rexnord Corp RRX.N, up 14.5%

** Stem Inc STEM.N, up 14.0%

The top three NYSE .PL.N percentage losers:

** Ranpak Holdings Corp PACK.N, down 25.4%

** BRC Inc BRCC.N, down 21.7%

** JELD-WEN Holding Inc JELD.N, down 19.4%

The top three Nasdaq .PG.O percentage gainers:

** AIFU Inc AIFU.OQ, up 105.5%

** Marin Software Inc MRIN.OQ, up 102.9%

** BloomZ Inc BLMZ.OQ, up 61.9%

The top three Nasdaq .PL.O percentage losers:

** NuCana PLC NCNA.OQ, down 70.3%

** bioAffinity Technologies Inc BIAF.OQ, down 47.4%

** Vivid Seats Inc SEAT.OQ, down 35.8%

** DoorDash Inc :
BUZZ - Falls after decision to buy Deliveroo, downbeat quarterly profit forecast  nL6N3RE0FU

** Hims & Hers Health Inc :
BUZZ - Rises after Q1 results beat  nL4N3RE1OI

** Newmont Corp :

** Barrick Gold Corp :

** AngloGold Ashanti PLC :

** Harmony Gold Mining Co Ltd :

BUZZ - Gold miners gain as safe-haven demand lifts bullion prices to 2-week peak  nL4N3RE0MN

** FirstSun Capital Bancorp  :
BUZZ - Gets 'overweight' rating as Stephens starts coverage  nL4N3RD1NK

** Ford Motor Co :
BUZZ - Falls after suspending annual forecast  nL4N3RE0NS

** Eaton Corp  :
BUZZ - J.P.Morgan raises Eaton PT driven by strong B2B growth  nL4N3RE0PW

** Lemonade Inc :
BUZZ - Jumps after raising annual forecasts  nL4N3RE0QK

** Vertex Pharmaceuticals Inc :
BUZZ - Falls after Q1 results miss  nL4N3RE1O7

**  Celsius Holdings Inc :
BUZZ - Falls after Q1 results miss estimates   nL6N3RE0EX

** Church & Dwight Co Inc :
BUZZ - Down after TD Cowen downgrades to "hold"  nL6N3RE0F7

** Datadog Inc :
BUZZ - Rises after beat-and-raise report  nL6N3RE0FG

** Constellation Energy Corp :
BUZZ - Falls after Q1 profit miss  nL4N3RE0VZ

** Cummins Inc :
BUZZ - Truist raises PT on Cummins after Q1 profit beats estimate  nL4N3RE0VM

** Broadridge Financial Solutions Inc :
BUZZ - Gets 'buy' rating as Needham starts coverage  nL4N3RE0VB

** SolarEdge Technologies Inc :
BUZZ - Rises on robust Q2 revenue forecast  nL4N3RE1MS

**  WK Kellogg Co :
BUZZ - Down after cutting annual sales, profit forecasts  nL6N3RE0GJ

** Marriott International Inc :
BUZZ - Rises after Q1 earnings beat estimates  nL4N3RE107

** FARO Technologies Inc :
BUZZ - Hits 3-year high on $920 million acquisition by AMETEK  nL6N3RE0KC

** Global Payments Inc :
BUZZ - Rises after reporting higher Q1 adjusted profit  nL4N3RE11M

**  Ball Corp :
BUZZ - Shares rise after raising annual profit forecast  nL6N3RE0GZ

** Jeld-Wen Holding Inc :
BUZZ - Shares tumble after tepid guide  nL6N3RE0GY

** Actuate Therapeutics Inc :
BUZZ - Rises as pancreatic cancer drug succeeds in mid-stage trial   nL6N3RE0H1

** IQVIA Holdings Inc :
BUZZ - Rises after beating first-quarter results estimates nL6N3RE0H7

** Mersana Therapeutics Inc :
BUZZ - Announces restructuring plans; shares fall nL6N3RE0H8

** Portillos Inc :
BUZZ - Shares dip after dour annual revenue, profit forecast  nL6N3RE0HC

** Sealed Air Corp :
BUZZ - Rises after upbeat quarterly results  nL6N3RE0I4

** Bank First Corp :

** First Savings Financial Group Inc :

** Lakeland Financial Corp :

** HBT Financial Inc :
BUZZ - US Midwest banks off to strong start in 2025 despite tariffs, Hovde Group says  nL6N3RE0GV

** Harmony Biosciences Holdings Inc :
BUZZ - Rises after quarterly results beat  nL4N3RE16Z

**  Krystal Biotech Inc :
BUZZ - Falls on Q1 results miss   nL6N3RE0JY

** Omnicell Inc :
BUZZ - Falls after 2025 profit forecast cut  nL4N3RE1JD

** Clorox Co :
BUZZ - Slides after disappointing results, downbeat sales forecast  nL6N3RE0KT

** Fidelity National Information Services Inc :
BUZZ - Falls on weak Q2 profit forecast  nL6N3RE0L3

** TransDigm Group Inc :
BUZZ - Tops Q2 profit estimates, CEO to retire; shares down  nL4N3RE17C

** PRA Group Inc :
BUZZ - Hits more than 1-year low after Q1 miss  nL4N3RE10H

** Duke Energy Corp :
BUZZ - Gains after upbeat first-quarter results  nL4N3RE1K9

**  Leidos Holdings Inc :
BUZZ - Rises after Q1 earnings beat estimates  nL4N3RE0MP

** Gartner Inc :
BUZZ - Gains after raising annual profit forecast  nL4N3RE1OP

**  Eli Lilly and Co :

** Abbvie Inc :

** Merck & Co Inc  :

** Gilead Sciences Inc  :

BUZZ - Drugmakers fall as Trump signals announcement on medicine costs  nL4N3RE1OX

 (Compiled by Rajarshi Roy and Anshuman Tripathy)

 ((Rajarshi.Roy@thomsonreuters.com))

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