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VRTX Vertex Pharmaceuticals News Story

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March 18 (Reuters) - Wall Street's main indexes slipped on Wednesday after data showed producer prices rose more than expected in February, prompting investors to price out any hopes for an interest rate cut by the Federal Reserve this year. .N

At 11:34 EDT, the Dow Jones Industrial Average .DJI was down 0.79% at 46,623.74. The S&P 500 .SPX was down 0.48% at 6,683.72, and the Nasdaq Composite .IXIC was down 0.46% at 22,376.73.

The top three S&P 500 .PG.INX percentage gainers:

** Williams-Sonoma Inc WSM.N, up 5.4%

** Ciena Corp CIEN.N, up 5.0%

** Akamai Technologies Inc AKAM.OQ, up 4.2%

The top three S&P 500 .PL.INX percentage losers:

** Trade Desk Inc TTD.OQ, down 5.7%

** Carvana Co CVNA.N, down 4.3%

** Comcast Corp CMCSA.OQ, down 4.1%

The top three NYSE .PG.N percentage gainers:

** Perfect Corp PERF.N, up 25.2%

** Andersen Group Inc ANDG.N, up 19.8%

** Tillys Inc TLYS.N, up 15.2%

The top three NYSE .PL.N percentage losers:

** Boyd Group Services Inc BGSI.N, down 11.8%

** Natuzzi SpA NTZ.N, down 9.9%

** Seabridge Gold Inc SA.N, down 9.7%

The top three Nasdaq .PG.O percentage gainers:

** Li Bang International Corporation Inc LBGJ.OQ, up 96.1%

** Swarmer Inc SWMR.OQ, up 91.2%

** Artelo Biosciences Inc ARTL.OQ, up 44.1%

The top three Nasdaq .PL.O percentage losers:

** Meiwu Technology Co Ltd WNW.OQ, down 47.4%

** Smart Powerr Corp CREG.OQ, down 38.1%

** Tokyo Lifestyle Co Ltd TKLF.OQ, down 29.1%

** Lululemon Athletica Inc LULU.O:
BUZZ - Drops on forecasting revenue below analysts' estimate nL6N4010GS

** Swarmer Inc SWMR.O:
BUZZ - Jumps a day after strong Nasdaq debut  nL6N4060HF

**  Gemini Space Station Inc GEMI.O:
BUZZ - Plunges after Citi downgrades to 'sell' nL6N4060X2

** DocuSign Inc DOCU.O:
BUZZ - Rises on upbeat FY27 revenue forecast, increased share buyback nL4N4060QR

** Ovid Therapeutics Inc OVID.O:
BUZZ - Rises as epilepsy drug shows clean safety nL4N4060SE

** T1 Energy Inc TE.N:
BUZZ - Rises after Norway grid assigns 50 MW to data center site  nL4N4060SO

** Constellation Brands Inc STZ.N:
BUZZ - Rises after Citigroup upgrades to 'buy' nL6N4060DY

** SAB Biotherapeutics Inc SABS.O:
BUZZ - Slips on $85 mln equity offering nL6N4060MQ

** Netflix Inc NFLX.O:
BUZZ - Citi resumes coverage on Netflix with 'buy', expects US price increases in Q4 nL6N4060KZ

** Arvinas Inc ARVN.O:
BUZZ - Up after early-stage trial shows drug lowers key Parkinson's marker nL4N4060WP

** CF Industries Holdings Inc CF.N:
BUZZ - Falls as Mizuho downgrades to 'underperform' nL6N4060PK

** Block Inc XYZ.N:
BUZZ - Rises after Truist Securities upgrades to 'buy' nL4N4060Y2

** Nebius Group NV NBIS.O:
BUZZ - Stabilizes after boosted $4 bln convertible bonds sale nL4N3ZZ153

** Artelo Biosciences Inc ARTL.O:
BUZZ - Jumps as it plans UK study of glaucoma drug nL4N4060ZB

** SL Green Realty Corp SLG.N:
BUZZ - Rises after Deutsche Bank upgrades to 'buy' nL4N4060Z0

** Starbucks Corp SBUX.O:
BUZZ - Shares dip as RBC downgrades to 'sector perform' nL6N4060QA

** i-80 Gold Corp IAUX.N:
BUZZ - Slides after unveiling $200 million convertible bonds offering nL6N4060PU

** SailPoint Inc SAIL.O:
BUZZ - Falls after forecasting Q1 revenue below estimates nL4N406110

** Trade Desk Inc TTD.O:
BUZZ - Falls amid downgrades and Publicis audit nL6N4060QK

** Hecla Mining Co HL.N:

** Coeur Mining Inc CDE.N:

** Endeavour Silver Corp EXK.N:

** Silvercorp Metals Inc SVM.N:

BUZZ - Silver miners fall as inflation fears bolster hawkish Fed bets nL6N4060RS

** Biomerica Inc BMRA.O:
BUZZ - Rises after securing first major European order for stomach infection test nL4N40612L

** Newmont Corp NEM.N:

** Gold Fields Ltd GFI.N:

** AngloGold Ashanti PLC AU.N:

** Harmony Gold Mining Co Ltd HMY.N:

BUZZ - Gold miners down as bullion prices edge lower on hawkish Fed bets nL4N40610Z

** Protagonist Therapeutics Inc PTGX.O:
BUZZ - Climbs after FDA approves oral psoriasis drug nL4N40613I

** MetaVia Inc MTVA.O:
BUZZ - Rises on regulatory nod to begin early-stage obesity trial  nL4N40613J

**  Fair Isaac Corp FICO.N:
BUZZ - Wells Fargo trims FICO's PT, sees limited risk from VantageScore nL4N406144

** RenovoRx Inc RNXT.O:
BUZZ - Rises after $10 mln private stock sale to fund cancer trial, device rollout nL4N406145

**AIM ImmunoTech Inc AIM.N:
BUZZ - Jumps after Japan grants patent for experimental cancer drug nL4N40614C

** Duolingo Inc DUOL.O:
BUZZ - Falls as Argus cuts to 'hold' nL6N4060P9

** CytomX Therapeutics Inc CTMX.O:
BUZZ - Drops on $250 mln equity raise nL6N4060TE

** Lucid Group Inc LCID.O:
BUZZ - Citi initiates Lucid coverage nL4N40615B

** Macy's Inc M.N:
BUZZ - Jumps on quarterly profit beat, tariff relief expectation nL6N4060TY

** Vertex Pharmaceuticals Inc VRTX.O:
BUZZ - Rises after brokerage upgrade on kidney disease drug data nL4N40611R

** U.S. Energy Corp USEG.O:
BUZZ - Shares rise after FID, EPC deal for Big Sky Carbon Hub project nL4N40616H

** Ormat Technologies Inc ORA.N:
BUZZ - Dips premarket after convertible bonds sale upsized to $875 mln  nL6N4060UF

** InspireMD Inc NSPR.O:
BUZZ - Rises after quarterly revenue beat nL4N4060QB

** Lantheus Holdings Inc LNTH.O:
BUZZ - Falls as FDA extends review of experimental cancer diagnostic  nL4N4060QE

** MiniMed Group Inc MMED.O:
BUZZ - Rises as FDA clears smartphone‑controlled insulin pump nL4N40618J

** General Mills Inc GIS.N:
BUZZ - Reaffirms annual forecasts, shares fall  nL6N4060WN

** Knight-Swift Transportation Holdings Inc  KNX.N:
BUZZ - UBS lifts Knight-Swift Transportation to 'buy' on tightening truckload market  nL4N4061DH

** AbbVie Inc ABBV.N:
BUZZ - Falls as J&J psoriasis pill raises competition risk nL4N4061EC

** SoFi Technologies Inc SOFI.O:
BUZZ - Rises day after short seller Muddy Waters' report  nL6N4060Y7

** Strategy Inc MSTR.O:
BUZZ - Falls after Citi cuts PT nL4N4061EH

** Intuitive Surgical Inc ISRG.O:
BUZZ - Falls after FDA flags stapler problem tied to four injuries, one death  nL4N4061F4

** Micron Technology Inc MU.O:
BUZZ - Hits record ahead of results on AI chip optimism  nL6N4060Y0

Index RICIndex namePercent change %
.SPXS&P 500-0.48
.SPLRCTS&P 500 Information Technology-0.15
.SPLRCUS&P 500 Utilities-0.42
.SPLRCDS&P 500 Consumer Discretionary-1.02
.SPLRCMS&P 500 Materials-1.47
.SPLRCIS&P 500 Industrials-0.03
.SPLRCLS&P 500 Communication Services (Sector)-0.23
.SPSYS&P 500 Financials-0.41
.SPLRCRS&P 500 Real Estate-0.84
.SPXHCS&P 500 Health Care-1.15
.SPLRCSS&P 500 Consumer Staples-1.68
.SPNYS&P 500 Energy0.15
(Compiled by Rajarshi Roy and Sumit Saha in Bengaluru) ((Rajarshi.Roy@thomsonreuters.com))

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