** Shares of Vertex Pharmaceuticals VRTX.O down 14% at $403.00 in extended trading
** Co says will not continue development of its experimental non-opioid painkiller as a solo treatment after it failed to meet the main goal of a mid-stage trial
** VRTX reports Q2 revenue of $2.96 billion, beating estimates of $2.91 billion - LSEG
** Co maintains annual forecast; adds forecast includes an immaterial cost impact from tariffs
** YTD, shares up 17% as of last close
(Reporting by Juveria Tabassum in Bengaluru)
((Juveria.Tabassum@thomsonreuters.com))