** Mizuho Securities initiates coverage on Vigil
Neuroscience VIGL.O with "buy" rating; sets PT of $15
** Brokerage sees significant upside to co's lead product
candidate, VGL101, being tested to treat a type of neurological
disease which affects the brain - VIGL
** VGL101 is being tested to treat adult-onset
leukoencephalopathy with axonal spheroids and pigmented glia
(ALSP) - co
** VIGL is "uniquely and ideally positioned" in the ALSP
treatment market as it is the only company developing a
therapeutic of any kind for ALSP - Mizuho
** Brokerage sees risk unadj. peak U.S., EU and Japan sales
of $2.9 bln for VGL101
** ALSP is a neurological condition caused by changes to
certain areas of the brain which usually begin in a person's
forties and worsen over time
** 6 of 7 brokerages rate the stock "buy" or higher, and 1
rate "hold"; their median PT is $20
** Stock lost ~21.3% since IPO in Jan 2022
(Reporting by Mariam Sunny)
((Mariam.ESunny@thomsonreuters.com;))