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U.S. STOCKS ON THE MOVE-Stoke Therapeutics, Foot Locker, Marvell

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Wall Street's main indexes climbed on Wednesday, with the S&P 500 and the Nasdaq touching record
highs driven by gains in technology stocks, while investors awaited comments from U.S. Federal
Reserve Chair Jerome Powell later in the day.  .N 
    
At  13:30 EST, the Dow Jones Industrial Average  .DJI  was up 0.38% at 44,873.45. The S&P 500
 .SPX  was up 0.32% at 6,069.26 and the Nasdaq Composite  .IXIC  was up 0.91% at 19,657.99.
 
The top three S&P 500  .PG.INX  percentage gainers:
** Salesforce Inc  CRM.N , up 8.9%
** ServiceNow Inc  NOW.N , up 5.8%
** Edwards Lifesciences Corp  EW.N , up 4.9%
The top three S&P 500  .PL.INX  percentage losers:
** Texas Pacific Land Corp  TPL.N , down 13.3%
** Marketaxess Holdings Inc  MKTX.O , down 7.2%
** Campbell's Co  CPB.OQ , down 5.7%
 
The top three NYSE  .PG.N  percentage gainers:
** Pure Storage Inc  PSTG.N , up 21.8%
** Container Store Group Inc  TCS.N , up 16.1%
** Lion Electric Co  LEV.N , up 14.2%
The top three NYSE  .PL.N  percentage losers:
** PSQ Holdings Inc  PSQH.N , down 33.7%
** Torrid Holdings Inc  CURV.N , down 27.9%
** Sos Ltd  SOS.N , down 13.6%
 
The top three Nasdaq  .PG.O  percentage gainers:
** Cyclerion Therapeutics Inc  CYCN.O , up 372.0%
** SMX (Security Matters) PLC  SMX.O , up 119.5%
** CN Energy Group Inc  CNEY.O , up 87.1%
The top three Nasdaq  .PL.O  percentage losers:
** Relmada Therapeutics Inc  RLMD.O , down 77.2%
** Mawson Infrastructure Group Inc  MIGI.O , down 58.1%
** Mondee Holdings Inc  MOND.O , down 32.1%
    
 ** Novavax Inc  NVAX.O :
BUZZ - Rises on $200 mln Czech manufacturing site sale to Novo Nordisk  urn:newsml:reuters.com:*:nL3N3N50NS
 
 ** Heron Therapeutics Inc  HRTX.O :
BUZZ - Jumps on favorable court ruling over Cinvanti patents  urn:newsml:reuters.com:*:nL3N3N50RG
    
 ** Crescent Energy Co  CRGY.N :
BUZZ - Down after $300 mln equity offering to fund Ridgemar deal  urn:newsml:reuters.com:*:nL6N3N50IN 
    
 ** Salesforce Inc  CRM.N :
BUZZ - Surges after revenue beats estimates, brokerages raise PT  urn:newsml:reuters.com:*:nL3N3N50R9
    
 **  Eli Lilly and Co  LLY.N :
BUZZ - Gains as weight-loss drug superior to rival Wegovy in trial  urn:newsml:reuters.com:*:nL3N3N50PF

 ** Marvell Technology Inc  MRVL.O :
BUZZ - Surges on upbeat Q4 forecast, propelling broader chip sector  urn:newsml:reuters.com:*:nL3N3N516J
    
 ** General Motors Co  GM.N :
BUZZ - Shares down after automaker to take more than $5 bln in charges on China operations
 urn:newsml:reuters.com:*:nL3N3N50S5
    
 ** Dollar Tree Inc  DLTR.O :
BUZZ - Rises on upbeat Q3 results  urn:newsml:reuters.com:*:nL3N3N50SR

 ** NexGen Energy Ltd  NXE.N :
BUZZ - Up after signing uranium deals with US utilities  urn:newsml:reuters.com:*:nL3N3N517P
    
 ** Atea Pharmaceuticals Inc  AVIR.O :
BUZZ - Rises as combo drug meets main goal in mid-stage study  urn:newsml:reuters.com:*:nL3N3N50TN
    
 ** Nutrien Ltd  NTR.N :
BUZZ - Raymond James upgrades Nutrien to 'outperform', raises PT  urn:newsml:reuters.com:*:nL3N3N50XG

 ** Relmada Therapeutics Inc  RLMD.O :
BUZZ - Slumps as depression drug unlikely to meet main trial goal  urn:newsml:reuters.com:*:nL3N3N50XQ
    
 ** Campbell's Co  CPB.N :
BUZZ - Down after Q1 sales miss  urn:newsml:reuters.com:*:nL3N3N51AH

 ** MSC Industrial Direct Co Inc  MSM.N :
BUZZ - Stifel downgrades MSC Industrial Direct rating to 'equal weight'  urn:newsml:reuters.com:*:nL3N3N50VU
    
 ** Robinhood Markets Inc  HOOD.O :
BUZZ - Rises after early November trading data  urn:newsml:reuters.com:*:nL5N3N516Z
 
 ** PSQ Holdings Inc  PSQH.N :
BUZZ - Retreats on direct stock offering after Tuesday's skyrocket  urn:newsml:reuters.com:*:nL6N3N50K3
    
 ** Archer-Daniels-Midland Inc  ADM.N :
BUZZ - BMO cuts PT on ADM, sees lower 2025 earnings  urn:newsml:reuters.com:*:nL3N3N50XR
    
 ** Nano Nuclear Energy Inc  NNE.O :
BUZZ - Rises on agreement with US Energy Dept for reactor testing  urn:newsml:reuters.com:*:nL3N3N511I
 
 ** JetBlue Airways Corp  JBLU.O :
BUZZ - Expects smaller annual revenue drop, shares rise  urn:newsml:reuters.com:*:nL3N3N5139
    
 ** Cracker Barrel Old Country Store Inc  CBRL.O :
BUZZ - Up after Q1 results beat  urn:newsml:reuters.com:*:nL3N3N50Z1
    
 ** Cross Country Healthcare Inc  CCRN.O :
BUZZ - Rises over 60% on $615 mln take-private deal  urn:newsml:reuters.com:*:nL3N3N514Z
 
 ** Royal Bank of Canada  RY.N :
BUZZ - Rises after Q4 profit beats estimates  urn:newsml:reuters.com:*:nL3N3N516W
    
 ** IREN Ltd  IREN.O :
BUZZ - Jumps after upsized $400 mln convertible priced  urn:newsml:reuters.com:*:nL6N3N50NC
    
 ** Generac Holdings Inc  GNRC.N :
BUZZ - Barclays starts coverage on Generac with 'equal weight' rating  urn:newsml:reuters.com:*:nL3N3N519F
    
 ** Stoke Therapeutics Inc  STOK.O :
BUZZ - Rises on FDA's 'breakthrough therapy' tag for epileptic disorder drug  urn:newsml:reuters.com:*:nL3N3N51A2
    
 ** Foot Locker Inc  FL.N :
BUZZ - Down after lowering annual sales, profit forecasts  urn:newsml:reuters.com:*:nL3N3N51AO
    
 ** Trimble Inc  TRMB.O :
BUZZ - Rises after J.P. Morgan upgrades to 'overweight'  urn:newsml:reuters.com:*:nL3N3N51C5
    
 ** Jabil Inc  JBL.N :
BUZZ - Stifel raises PT on Jabil ahead of Q1 results  urn:newsml:reuters.com:*:nL3N3N51CY
    
 ** Marriott International Inc  MAR.O :
BUZZ - Truist Securities raises PT on Marriott International  urn:newsml:reuters.com:*:nL3N3N51D4
    
 ** Airbnb Inc  ABNB.O :
BUZZ - Truist Securities cuts PT on Airbnb  urn:newsml:reuters.com:*:nL3N3N51DR
    
 The 11 major S&P 500 sectors:
 
 Index RIC     Index name                       Percent change %
  .SPX         S&P 500                          0.32 
  .SPLRCT      S&P 500 Information Technology                    1.36
  .SPLRCU      S&P 500 Utilities                                -0.23
  .SPLRCD      S&P 500 Consumer Discretionary                    0.64
  .SPLRCM      S&P 500 Materials                                -0.94
  .SPLRCI      S&P 500 Industrials                               0.08
  .SPLRCL      S&P 500 Communication Services                    0.44
               (Sector)                         
  .SPSY        S&P 500 Financials                               -0.59
  .SPLRCR      S&P 500 Real Estate                               -0.4
  .SPXHC       S&P 500 Health Care                               0.05
  .SPLRCS      S&P 500 Consumer Staples                         -0.39
  .SPNY        S&P 500 Energy                                   -2.82
 

 (Compiled by Rajarshi Roy and Puyaan Singh)
 ((Rajarshi.Roy@thomsonreuters.com))

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