(Updates)
** U.S.-listed shares XRTX.O of XORTX Therapeutics Inc up
34.1% at $1.05, set for biggest one-day pct gain in more than
six months
** Drug developer says its experimental drug was shown to be
safe and effective in treatment of a rare disease called
autosomal dominant polycystic kidney disease (ADPKD)
** ADPKD is characterized by expansion of fluid-filled cysts
in the kidneys
** The drug candidate, xorlo, is an oral formulation of
oxypurinol which inhibits the production of uric acid, company
says
** The drug's oral formulation helps in increased absorption
of oxypurinol - XRTX
** Including session moves, company's shares down ~42% in
the past 12 months
(Reporting by Mariam E Sunny)
((Mariam.ESunny@thomsonreuters.com))