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ABOS — Acumen Pharmaceuticals News Story

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Acumen Pharma soars after Alzheimer's drug well-tolerated in early stage study

** Shares of Alzheimer's drug developer Acumen
Pharmaceuticals Inc's  ABOS.O  shares up 43.3% at ~$9
    ** Co on Sunday said its drug candidate, ACI193 was well
tolerated in a first in human early stage trial testing 62
patients with early Alzheimer's disease
    ** The experimental drug that targets a novel form of the
toxic protein beta amyloid in the brain passed an early safety
test and will advance to a larger trial, company says
    ** The drug's target is similar to that of Biogen Inc    
 BIIB.O  and Eisai Co Ltd's  4523.T  recently-approved Leqembi,
which hits another soluble, toxic form of the protein in the
brain 
    ** Co adds people who got higher doses of the drug also
showed a reduction in amyloid plaque after 6 to 12 weeks
    ** While no drug-related serious adverse events occurred,
8.3% or 5 treated patients developed a brain swelling condition
known as ARIA-E associated with amyloid-targeting treatments
    ** As of last close, stock up 16.3% this year

 (Reporting by Pratik Jain in Bengaluru)
 ((Pratik.Jain@thomsonreuters.com;))

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