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ABOS — Acumen Pharmaceuticals News Story

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Acumen sinks after Alzheimer's drug fails mid-stage study

BUZZ-Acumen sinks after Alzheimer's drug fails mid-stage study

** Shares of Acumen Pharmaceuticals ABOS.O plunge 78.2% to $0.50 premarket

** The biotech firm says its experimental Alzheimer's disease drug sabirnetug failed the main goal of a mid-stage study, showing no meaningful benefit in slowing memory and functional decline versus placebo

** Co says key secondary measures, including CDR-SB, also failed to reach statistical significance

** Drug reduced amyloid plaque levels in the brain, but that did not translate into clinical benefit

** Co plans to stop development of sabirnetug, end the study's extension phase and implement cash-conservation measures

** As of last close, stock up ~9% YTD


(Reporting by Sahil Pandey in Bengaluru)

((Sahil.Pandey@thomsonreuters.com))

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