** Shares of anti-infective drug developer Aridis
Pharmaceuticals Inc ARDS.O down 35% at $0.79 premarket, top
pct loser across U.S. exchanges
** Company's investigational antibody drug to treat
ventilator associated pneumonia, a lung infection that develops
in a person who is on ventilator, fails to meet main efficacy
goal in a late-stage study
** But main measures of safety and tolerability achieved,
with no drug-related serious adverse events - ARDS
** COVID-19 pandemic and subsequent conflict in Eastern
Europe limited patient enrollment in study - company
** Aridis plans to initiate a second late-stage study to
confirm drug's efficacy and safety, after discussing the current
study results with regulatory authorities
** Stock has declined 40% in the last 12 months
(Reporting by Aditya Samal)
((Aditya.Samal@thomsonreuters.com))