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Inovio says Zika vaccine shows response in mice (updated)

(Adds details, shares) 
    Feb 17 (Reuters) - Drug developer Inovio Pharmaceuticals Inc 
 INO.O  said preclinical testing of its vaccine for Zika virus 
induced robust and durable response in mice and it expected to 
test the vaccine in humans before the end of 2016. 
    The company's shares rose 11.1 percent to $7.30 in premarket 
trading on Wednesday. 
    Zika, whose symptoms include mild fever and rash, has been 
linked to brain damage in thousands of babies in Brazil.  
    There is no proven vaccine or treatment for the Zika virus, 
a close cousin of the viruses that cause dengue and chikungunya. 
    Inovio said on Wednesday that mice given its vaccine showed 
development of antibodies and generated response from T-cells, 
which play an important role in immunizing the body.  
 urn:newsml:reuters.com:*:nGNXMMJAGa 
    An estimated 80 percent of people infected have no symptoms, 
making it difficult for pregnant women to know whether they have 
been infected.    
    Inovio said it was developing the vaccine with GeneOne Life 
Sciences Inc  011000.KS  and academic collaborators. 
     
     
 
 (Reporting by Amrutha Penumudi in Bengaluru; Editing by Kirti 
Pandey) 
 ((penumudi.amrutha@thomsonreuters.com; within U.S. +1 646 223 
8780 outside U.S. +91 80 6749 4486; Reuters Messaging: 
penumudi.amrutha.thomsonreuters.com@reuters.net)) 
 
Keywords: HEALTH ZIKA/INOVIO PHARMA

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