Factbox: The race for a coronavirus vaccine
20/07/2020 16:33
(Adds Osaka University, Kentucky Bioprocessing, Vaxine, Medigen; Updates CureVac, J&J, GSK)
July 29 (Reuters) - More than 150 vaccines are being developed and tested around the world to stop the COVID-19 pandemic, with 25 in human
clinical trials, according to the World Health Organization.
The following list tracks the latest developments from major drugmakers and research institutes that have started human trials for their
vaccine candidates.
For a separate FACTBOX on treatments under development, click here: urn:newsml:reuters.com:*:nL4N2BH35E
Company State of play Development phase Story date/link
AstraZeneca Plc AZN.L Vaccine produces immune response in early-stage Final stage study in 1,077 healthy July 20 urn:newsml:reuters.com:*:nL5N2ER3V8
trials; Late-stage trials currently underway in adults
Brazil and South Africa and due to start in the
U.S. ; Over a million doses possible by September
Sinopharm 1099.HK The Chinese state-owned company is developing two Final stage trials in Abu Dhabi, testing July 16 urn:newsml:reuters.com:*:nL5N2EN20H
vaccines, one of which has shown promise in humans. up to 15,000 volunteers.
Pfizer Inc PFE.N and Vaccine produced virus-neutralizing antibodies in Begins pivotal global study to evaluate July 27 urn:newsml:reuters.com:*:nL3N2EY4HS
BioNTech SE 22UAy.F early-stage trials in U.S. and Germany; Pfizer aims lead COVID-19 vaccine candidate; Study
for about 1.3 billion doses by the end of 2021 aims to enroll 30,000 volunteers
Moderna Inc MRNA.O Vaccine could be ready for widespread use by end of 30,000-subject final stage trial to July 27 urn:newsml:reuters.com:*:nL3N2EY2MN
2020, company says on track to deliver up to 1 demonstrate it is safe and effective
billion doses a year, beginning 2021 began on July 27.
Sinovac Biotech Ltd SVA.O The China-based vaccine maker has released positive Final-stage trials. July 6 urn:newsml:reuters.com:*:nL1N2ED0JA
preliminary results from early-stage trials of its
vaccine.
CanSino Biologics 6185.HK Early results showed the China-based company's Mid-stage trial. July 20 urn:newsml:reuters.com:*:nL3N2ER36S
vaccine is safe. China's military has received the
greenlight to use the vaccine.
Inovio Pharma INO.O Vaccine candidate, found to be safe, induced immune Mid-stage testing. June 30 urn:newsml:reuters.com:*:nL4N2E737Q
responses in healthy volunteers in an early stage
study
Not applicable Researchers at Institute of Medical Biology at Mid-stage trials. June 21 urn:newsml:reuters.com:*:nL4N2DY03I
Chinese Academy of Medical Sciences are testing a
coronavirus vaccine.
Chongqing Zhifei Biological The Chinese company's unit Anhui Zhifei Longcom Mid-stage trial. July 10 urn:newsml:reuters.com:*:nL4N2E018D
Products 300122.SZ Biopharmaceutical has begun human trials.
Bharat Biotech Vaccine approved for human trials in India. Early- to mid-stage trials to start in June 29 urn:newsml:reuters.com:*:nL4N2E70F6
July
Johnson & Johnson JNJ.N In talks with Japan, Bill and Melinda Gates Early stage trials to start in July, July 16 urn:newsml:reuters.com:*:nL5N2EO2Y0
Foundation, and the European Union for vaccine late-stage study planned for September.
allocations, Reuters reported.
Novavax Inc NVAX.O The U.S. government has awarded $1.6 billion to Early-stage testing. July 7 urn:newsml:reuters.com:*:nL1N2EE0HB
test and manufacture its experimental vaccine.
GlaxoSmithKline Plc GSK.L Partnered with Sanofi SA SASY.PA to develop a Early stage trials to begin in July 29 urn:newsml:reuters.com:*:nP6N2DU00V
vaccine. September.
CureVac German biotech expects data in September or Early-stage trial. July 24 urn:newsml:reuters.com:*:nL3N2EV38S
October; files for IPO in U.S.
Clover Biopharmaceuticals The Chinese developer received $66 million in Early-stage trials. July 8 urn:newsml:reuters.com:*:nL4N2DW1WI
investment from an epidemic response group.
Not applicable Scientists at Imperial College London are running Early-stage trials. June 15 urn:newsml:reuters.com:*:nL8N2DS5JI
trials of a potential coronavirus vaccine.
Genexine Inc 095700.KQ South Korea's Genexine has begun human trials of Early-stage trials. June 19 urn:newsml:reuters.com:*:nL4N2DW1T3
its vaccine.
Not applicable The Gamaleya Research Institute in Russia has begun Early-stage trials July 13 urn:newsml:reuters.com:*:nL5N2EK3H0
human trials of an experimental vaccine, with
results expected in August.
Walvax Biotechnology Co Trials sponsored by the China-based company, along Early-stage studies. June 24 urn:newsml:reuters.com:*:nL1N2E11Q8
300142.SZ with a Chinese military research institute, have
begun.
Medicago The Canadian company is studying a plant-based Early-stage trials. July 14 urn:newsml:reuters.com:*:nL3N2EK3DD
vaccine.
Cadila Healthcare Ltd Plans to finish late-stage trials by early 2021. Early-stage trials. July 17 urn:newsml:reuters.com:*:nL5N2EO1QP
CADI.NS
Not applicable University of Queensland began human trials in Early-stage testing. July 14 (https://bit.ly/2Eo5iDg)
collaboration with Australian biotech company CSL
CSL.AX
Arcturus Therapeutics Gets approval to begin clinical trials for its Early-stage testing. July 21 urn:newsml:reuters.com:*:nASA00XE2
ARCT.O and Duke-NUS COVID-19 vaccine candidate, LUNAR-COV19
Osaka University, AnGes, A single-center trial in 30 healthy volunteers Early-stage testing. June 29 (https://bit.ly/3gaEiFB)
Takara Bio 4974.T
Kentucky BioprocessingInc Expects to begin trial of vaccine candidate in 180 Early-stage testing. July 28 (https://bit.ly/2BJDU1M)
adults on July 31
Vaxine Pty Ltd/Medytox Australian biotech expects to start mid-stage Early-stage testing. July 29 urn:newsml:reuters.com:*:nL3N2F034D
trials in next few weeks after positive results
from the first stage human study
Medigen Vaccine Biologics Expects to begin early-stage study in 45 people on Early-stage trial. July 27 (https://bit.ly/2XbnAOS)
Corp/NIAID/Dynavax Sept 1. Not yet recruiting
(Reporting by Vishwadha Chander and Manas Mishra in Bengaluru; Editing by Sriraj Kalluvila. Shailesh Kuber and Maju Samuel)
((Manas.Mishra@thomsonreuters.com; www.twitter.com/Manasmishra24; within U.S. +1 646 223 8780, outside U.S. +91 806749 2709;))
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