** Brokerage Guggenheim says Sage Therapeutics SAGE.O is
its top pick after initiating coverage on 11 companies focused
on developing treatments for inflammation and central nervous
system disorders
** In light of abating growth in several large-therapeutic
categories, Guggenheim analysts say they expect large-cap
companies to remain acquisitive in the central nervous system
space and advise investors to overweight small-mid-cap names
** Brokerage says Sage's depression drugs could be
paradigm-changing for patients and sees "more mileage left" in
co's stock despite a ~50 pct YTD rise; sets "buy" rating
** Guggenheim also "buy" rated on AnaptysBio Inc ANAB.O ,
Argenx SE ARGX.BR , Global Blood Therapeutics GBT.O , GW
Pharmaceuticals GWPH.O , among others
** However, brokerage cautious on large-cap companies
Regeneron REGN.O , Alexion ALXN.O and Biogen BIIB.O over
growth concerns, competition fears and lack of conviction in
development candidates
Company name Guggenheim's Price
Rating target
AnaptysBio Inc Buy $135
Argenx SE Buy $157
Global Blood Therapeutics Buy $75
GW Pharmaceuticals Buy $178
Inflarx NV IFRX.O Buy $65
Ra Pharmaceuticals Inc Buy $48
RARX.O
Zogenix Inc ZGNX.O Buy $70
Sage Therapeutics Buy $205
Alexion Pharmaceuticals Neutral $135
Biogen Inc Neutral $325
Regeneron Neutral $425
(Reporting by Manas Mishra in Bengaluru)
((Reuters Messaging:
manas.mishra.thomsonreuters.com@reuters.net))