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Wall Street's main indexes dropped on Monday, led by declines in software and financials, as uncertainty around tariffs intensified after President Donald Trump announced new levies following a Supreme Court ruling last week.  .N

At  1330 EST, the Dow Jones Industrial Average .DJI was down 1.27% at 48,994.72.The S&P 500 .SPX was down 0.81% at 6,853.75, and the Nasdaq Composite .IXIC was down 0.89% at 22,681.42.

The top three S&P 500 .PG.INX percentage gainers:

** PayPal Holdings Inc PYPL.OQ, up 6.7%

** Sandisk Corp SNDK.OQ, up 5.2%

** Albemarle Corp ALB.N, up 4.5%

The top three S&P 500 .PL.INX percentage losers:

** Datadog Inc DDOG.OQ, down 10.4%

** CrowdStrike Holdings Inc CRWD.OQ, down 9.9%

** Applovin Corp APP.OQ, down 9.4%

The top three NYSE .PG.N percentage gainers:

** Allurion Technologies Inc ALUR.N, up 59.6%

** Enhabit Inc EHAB.N, up 22.5%

** Veris Residential Inc VRE.N, up 12.2%

The top three NYSE .PL.N percentage losers:

** LiveWire Group Inc LVWR.N, down 18.3%

** Stepan Co SCL.N, down 18.2%

** Novo Nordisk A/S NVO.N, down 16.0%

The top three Nasdaq .PG.O percentage gainers:

** Tian Ruixiang Holdings Ltd TIRX.OQ, up 99.8%

** Arcellx Inc ACLX.OQ, up 77.5%

** Vanda Pharmaceuticals Inc VNDA.OQ, up 44.4%

The top three Nasdaq .PL.O percentage losers:

** Gossamer Bio Inc GOSS.OQ, down 84.4%

** United Homes Group Inc UHG.OQ, down 51.5%

** Blue Hat Interactive Entertainment Technology BHAT.OQ, down 48.6%

** Eli Lilly and Co LLY.N:
BUZZ -  Up as rival Novo Nordisk's obesity drug underperforms in trial nL4N3ZJ1DH

** Coinbase Global Inc COIN.O:

** Bitfarms Ltd BITF.O:

** Riot Platforms Inc RIOT.O:

** MARA Holdings Inc MARA.O:

BUZZ - Crypto stocks down as bitcoin, ether fall on US trade uncertainty nL4N3ZJ0JB

** Workday Inc WDAY.O:

** DocuSign Inc DOCU.O:

** Monday.com Ltd MNDY.O:

** Freshworks Inc FRSH.O:
BUZZ - Jefferies downgrades software stocks amid AI disruption fears nL6N3ZJ0CL

** VF Corp VFC.N:
BUZZ - Falls after J.P. Morgan cuts to 'underweight' nL6N3ZJ0EN

** Domino's Pizza Inc DPZ.O:
BUZZ - Rises after US sales top estimates  nL6N3ZJ0GY

** Arcellx Inc ACLX.O:
BUZZ - Hits record high as Gilead agrees to up to $7.8 bln acquisition nL4N3ZJ1EJ

** Hecla Mining Co HL.N:

** Coeur Mining Inc CDE.N:

** Endeavour Silver Corp EXK.N:

** Wheaton Precious Metals Corp WPM.N:

BUZZ - Silver miners gain as metal prices edge higher on weak US dollar nL4N3ZJ0MK

** MoonLake Immunotherapeutics MLTX.O:
BUZZ - Rises as spine‑inflammation drug shows benefit, secures new funding  nL4N3ZJ0MM

** Novo Nordisk A/S NVO.N:
BUZZ - Slumps to almost 5-yr lows after obesity drug trial disappoints investors nL8N3ZJ0N8

** Deere & Co DE.N:
BUZZ - Jefferies downgrades Deere to 'underperform'; shares fall   nL6N3ZJ0DB

** Vanda Pharmaceuticals Inc VNDA.O:
BUZZ - Jumps as US FDA approves new antipsychotic pill nL4N3ZJ0NG

** Merck & Co Inc MRK.N:
BUZZ - Rises as drugmaker revamps human health business  nL4N3ZJ0PO

** Leidos Holdings Inc LDOS.N:
BUZZ - Jefferies trims Leidos PT on soft 2026 outlook nL4N3ZJ0PA

** Fortune Brands Innovations Inc FBIN.N:
BUZZ - Rises on reported activist investor stake nL6N3ZJ0HT

** Freshpet Inc FRPT.O:
BUZZ - Falls on annual profit forecast below estimates  nL6N3ZJ0I9

** ImmunityBio Inc IBRX.O:
BUZZ - Rises as cancer drug therapy sales surge, global approvals expand nL4N3ZJ0RA

** Consolidated Edison Inc ED.N:
BUZZ - Jefferies raises PT on Consolidated Edison as "steady eddy" approach pays off nL6N3ZJ0JN

** InMode Ltd INMD.O:
BUZZ - Slips after board committee rejects deal proposals  nL4N3ZJ0SP

** CenterPoint Energy Inc CNP.N:
BUZZ - Drops from record after unveiling $550 mln convertible deal nL6N3ZJ0JJ

** Veris Residential Inc VRE.N:
BUZZ - Jumps on $3.4 billion takeover by Affinius-led consortium  nL4N3ZJ0SR

** GeneDx Holdings Corp WGS.O:
BUZZ - Shares rise after Q4 results beat estimates nL4N3ZJ0TF

** Alphabet Inc GOOGL.O:
BUZZ - Wells Fargo highlights Alphabet's compute capacity edge nL6N3ZJ0K2

** Select Medical Holdings Corp SEM.N:
BUZZ - Rises as Ortenzio submits buyout proposal nL4N3ZJ0U8

** PPL Corp PPL.N:
BUZZ - Dips after announcing $1 bln equity units offering nL6N3ZJ0KP

** York Space Systems Inc YSS.N:
BUZZ - Rises as IPO research quiet period ends nL4N3ZJ139

** FTC Solar Inc FTCI.O:
BUZZ - Gains after clinching 3-year South Africa supply deal nL4N3ZJ0W4

 ** Packaging Corp of America PKG.N:

** Smurfit Westrock PLC SW.N:

 ** International Paper Co IP.N:
BUZZ - US paper and packaging firms fall as containerboard prices slide nL4N3ZJ0UN

 ** Dominion Energy Inc D.N:
BUZZ - Down after forecasting 2026 profit below estimates nL6N3ZJ0L6

 ** JPMorgan Chase & Co JPM.N:
BUZZ - Disclosure on Trump's accounts reinforces debanking dispute risk, WellsFargo analyst says nL6N3ZJ0HH

 ** Enhabit Inc EHAB.N:
BUZZ - Rises after $1.1 billion go-private deal with Kinderhook nL4N3ZJ0YO

 ** Itron Inc ITRI.O:
BUZZ - Slips after $600 mln convertible bonds sale plans unveiled nL6N3ZJ0LW

 ** First Solar Inc FSLR.O:
BUZZ - Needham lifts PT on US solar panel maker First Solar nL4N3ZJ0WU

 ** Gossamer Bio Inc GOSS.O:
BUZZ - Falls after experimental lung condition drug fails in trial nL4N3ZJ0TN

 ** Vertical Aerospace Ltd EVTL.N:
BUZZ - Falls after Raymond James cuts rating nL4N3ZJ0YP

 ** Teck Resources Ltd TECK.N:
BUZZ - Benchmark raises Teck Resources' PT on higher byproduct prices nL4N3ZJ0ZB

** Centrus Energy Corp LEU.N:
BUZZ - Needham cuts PT on Centrus Energy; cites higher capital needs, shipment‑timing impact nL4N3ZJ0YL

** J M Smucker Co SJM.N:

** General Mills Inc GIS.N:
BUZZ - BofA upgrades rating for J M Smucker, downgrades General Mills  nL6N3ZJ0KT

** Imperial Oil Ltd IMO.N:
BUZZ - RBC lowers Imperial Oil rating to 'underperform' nL4N3ZJ10M

** Ethos Technologies Inc LIFE.O:
BUZZ - Rises as IPO research quiet period ends nL4N3YV1TA

** PENN Entertainment Inc PENN.O:
BUZZ - Shares falls; settles with activist investor, appoints three new directors nL4N3ZJ13H

** Newmont Corp NEM.N:

** Gold Fields Ltd GFI.N:

** Harmony Gold Mining Co Ltd HMY.N:

** Sibanye Stillwater Ltd SBSW.N:

BUZZ - Gold miners gain on uncertainty over Trump's tariff plans nL6N3ZJ0OW

** Booking Holdings Inc BKNG.O:
BUZZ - Falls after brokerages cut PT  nL4N3ZJ15Q

** Goldman Sachs Group Inc GS.N:

** Morgan Stanley MS.N:

** Wells Fargo & Co WFC.N:

** JPMorgan Chase & Co JPM.N:
BUZZ - Financials start week on the backfoot as sentiment weakens nL6N3ZJ0PM

** PicPay Holdings Netherlands BV PICS.O:
BUZZ - Rises as IPO research quiet-period ends nL4N3ZJ16V

** AbbVie Inc ABBV.N:
BUZZ - Rises; co plans $380 mln investment in new drug ingredient plants nL4N3ZJ17R

** Real Asset Acquisition Corp RAAQ.O:
BUZZ - Jumps on deal to take IQM Quantum public  nL6N3ZJ0R5

** PayPal Holdings Inc PYPL.O:
BUZZ - Jumps after report firm attracts takeover interest nL6N3ZJ0S9

** Grupo Aeroportuario del Pacifico SAB de CV PAC.N:

** Grupo Aeromexico SAB de CV AERO.N:

BUZZ - Mexican airlines, airport operators down after crime boss killed  nS0N3YN043

** BlackRock Inc BLK.N:
BUZZ - UBS upgrades BlackRock on stronger long‑term fee growth outlook nL4N3ZJ199

** Texas Pacific Land Corp TPL.N:
BUZZ - Gains after KeyBanc raises PT on data center, water trends nL4N3ZJ1G7

Index RICIndex namePercent change %
.SPXS&P 500-0.82
.SPLRCTS&P 500 Information Technology-0.67
.SPLRCUS&P 500 Utilities0.44
.SPLRCDS&P 500 Consumer Discretionary-2.52
.SPLRCMS&P 500 Materials0
.SPLRCIS&P 500 Industrials-1.08
.SPLRCLS&P 500 Communication Services (Sector)-0.6
.SPSYS&P 500 Financials-2.98
.SPLRCRS&P 500 Real Estate0.23
.SPXHCS&P 500 Health Care1.01
.SPLRCSS&P 500 Consumer Staples1.4
.SPNYS&P 500 Energy0.51
(Compiled by Rajarshi Roy and Kritika Lamba) ((Rajarshi.Roy@thomsonreuters.com))

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