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RCS - Berlin Cures Holding - Changes to Board of Directors

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RNS Number : 9318T  Berlin Cures Holding AG  26 June 2024

Issuer: Berlin Cures Holding AG / Key word(s): Personnel

Berlin Cures announces changes to Board of Directors to further propel the
development of BC 007

26.06.2024

The issuer is solely responsible for the content of this announcement.

·     Berlin Cures announces the appointment of Craig T. Basson, Gerrard
Terlouw, and Oliver von Stein to its Board of Directors, succeeding Ulf Berg,
Georg Nederegger, and Johannes Müller.

·     New board members will strengthen preparation for the Long COVID
Phase II trial data read-out and shape the future development strategy, as
well as business development and licensing.

·     Cardiovascular disease and Long COVID remain strategic priorities,
with the in-house platform technology offering further opportunities.

Berlin, Germany, 26 June 2024 - Berlin Cures, a pioneer in the use of
aptamer-based therapeutics in autoimmune diseases, announced important changes
to its Board of Directors today. The aim is to further drive the development
of the company's lead drug candidate BC 007, currently in a Phase II clinical
trial for Long COVID. Berlin Cures welcomes three distinguished new members
who bring a wealth of knowledge and strategic insight to its board of
directors:

Craig T. Basson, MD, PhD, is a renowned physician-scientist with more than 25
years of experience in cardiovascular medicine. His research and leadership
roles in the pharmaceutical industry have provided him with extensive
experience in drug development with a particular focus on cardiovascular
disease. Gerrard Terlouw, PhD, MBA is an experienced corporate and business
development executive with more than 20 years of leadership experience in the
pharmaceutical industry. He has a proven track record of successful licensing
and acquisition deals across multiple therapeutic areas. In addition, Berlin
Cures' CEO Oliver von Stein, PhD, will join the Board of Directors, bringing
his extensive management experience from various executive roles in the
pharmaceutical industry and from leading Berlin Cures as CEO.

Following these new appointments, Ulf Berg, Johannes Müller and Georg
Nederegger will step down from the Board of Directors with immediate effect
after many successful years. Johannes Müller will continue in his role as
Chief Science Officer as part of Berlin Cures' management team and will
continue to drive the company's research activities.

"We are delighted to welcome Craig Basson, Gerrard Terlouw and Oliver von
Stein to our Board of Directors. Their invaluable experience in clinical
development, immunology, cardiovascular disease and business development will
be instrumental as we continue to advance our BC 007 platform. Together, we
are poised to make a significant impact on the lives of patients worldwide",
states Rainer Böhm, Chairman of the Board of Berlin Cures. "On behalf of the
entire board and management team, I would like to express my deep gratitude to
Ulf Berg, Johannes Müller, and Georg Nederegger for their vital support over
the past years. Their expertise and guidance have been instrumental in
achieving Berlin Cures' latest milestones, such as the current trials in Long
COVID and heart failure. As we remain in close contact, we will continue to
benefit from their experience and advice."

Berlin Cures is at the forefront of developing innovative aptamer-based drugs
to neutralize pathogenic functional autoantibodies (fAABs) that contribute to
a variety of autoimmune diseases, including Long COVID, heart failure,
glaucoma, ME/CFS and many more. The company's lead drug candidate BC 007
(Rovunaptabin) targets these harmful fAABs and hence has the potential to
address the root cause of various autoimmune diseases. The company is
currently conducting a Phase II trial with BC 007 in the indication Long
COVID, with initial results expected in Q4 2024, and has already completed a
Phase IIa study with BC 007 in heart failure.

In parallel, Berlin Cures is preparing for a subsequent Phase III study in
Long COVID which will be crucial for market approval. The company is actively
seeking funding partners to be able to initiate Phase III as soon as possible
following a successful outcome of Phase II.

Please find further information about the Board of Directors here
(https://urldefense.com/v3/__https:/www.berlincures.com/en/about*cblock_270__;Iw!!KZXpRQ!WobcgpcJgIWQxQHYQRjNl5sEK6OYMChMrdFEOTvdP0ln4j3FXe0oAO6N7GJMcZdRnRmXbc7kFIDhnV_gCVETEwcgzKY$)
.

About Berlin Cures:
The Berlin Cures team has dedicated over two decades to the research of
functional autoantibodies (fAABs) and has successfully identified a molecule
capable of effectively neutralizing these. Promising preclinical results have
been observed for BC 007. In a recently completed Phase IIa trial with
patients with chronic heart failure, BC 007 demonstrated long-term
autoantibody neutralization after a single dose resulting in significant
improvement in cardiac function. Its potential as an effective therapy for
Long COVID was realized when tests on sera from Long COVID patients proved
positive for fAABs, supported by clinical observations in four case studies.
By addressing the underlying cause of fAAB-associated diseases with this
unique biotechnology, Berlin Cures emerges as one of the pioneering entities
committed to addressing this critical issue at its core.

Berlin Cures is currently running a Phase II clinical trial with BC 007 in the
indication Long COVID, an acute and escalating global health problem, to
obtain meaningful and robust results on efficacy and tolerability. Initial
results are expected in Q4 2024.

Contact:
FGS Global

E-Mail: berlincures-eu@fgsglobal.com (mailto:berlincures-eu@fgsglobal.com)
 

 

 

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