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Novartis' breast cancer drug cuts risk of death by 19% after six years, data shows

Novartis' breast cancer drug cuts risk of death by 19% after six years, data shows 

By Bhanvi Satija

- Swiss drugmaker Novartis' NOVN.S drug Kisqali helped extend survival for women with a form of high-risk, early-stage breast cancer, cutting their risk of death by 19% after six years, according to trial data presented at the European Society for Medical Oncology congress in Madrid on Friday.

  • At six years, 91.9% of women who received Kisqali and hormone therapy were alive compared with 89.7% of those who received hormone therapy alone

  • The survival gap grew from 1.2 percentage points at five years to 2.1 points at six years.

  • The initial expectation was that it would take about 10 years of follow-up to show a survival difference. "Turns out we’re seeing a difference even sooner," said UCLA's Dennis Slamon, the trial's lead investigator

  • Kisqali works by slowing cancer cells rather than killing them immediately. The longer cancer cells stay frozen, the more likely they are to permanently stop dividing and die

  • The drug is already approved in the US and EU for patients with stage 2 or 3 breast cancer at high risk of recurrence.

  • Analysts expect sales of the drug to be about $7 billion for this year, according to Visible Alpha estimates.


(Reporting by Bhanvi Satija;Editing by Elaine Hardcastle)

((Bhanvi.Satija@thomsonreuters.com; +44 7920644259;))

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