Overview
UK biotech firm reported half-year loss as R&D spending continued on autoimmune and cancer pipeline
Company restarted Phase 2-enabling toxicology for SDC-1801 after confirming earlier safety findings were unrelated
Cash at 31 Dec 2025 was £2.5 mln, with ongoing activities funded from existing resources
Outlook
Company expects dosing phase of SDC-1801 toxicology programme to complete in mid-2026
Sareum anticipates full Phase 2-enabling regulatory package for SDC-1801 by year-end
Company plans to advance portfolio through targeted business development and partnerships
Result Drivers
FORMULATION AND CMC DEVELOPMENT - Ongoing work to optimise SDC-1801 formulation and manufacturing contributed to R&D spend
NEUROSCIENCE COLLABORATION - Continued investment in TYK2 neuroscience discovery programme with Receptor.AI added to period costs
Company press release: ID:nRSL3116Wa
Key Details
Metric
Beat/Miss
Actual
Consensus Estimate
H1 EPS
-GBP 0.01
H1 EBIT
-GBP 1.82 mln
H1 Pretax Profit
-GBP 1.85 mln
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(This story was created using Reuters automation and AI based on LSEG and company data. It was checked and edited by a Reuters journalist prior to publication.)