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7643 — Daiichi News Story

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MacroGenics surges as Citigroup upgrades to 'buy', lifts PT

** Shares of drug developer MacroGenics  MGNX.O  rise 14.8%
to a one-year high of $10.6 after brokerage Citigroup upgrades
rating to "buy" from "neutral"
    ** Citi raises PT to $13 from $7, citing execution across
its pipeline of cancer drugs, increasing investment and interest
in targeted cancer drugs called antibody-drug conjugate (ADC)
    ** New PT represents an upside of 40.8% to MGNX's last close
    ** Citi says mid-stage data from MGNX's drug candidate,
vobra duo, exceeded expectations and "appears competitive" to
Daiichi's  7643.T  cancer drug candidate that targets the same
mutation in tumors  
    ** MGNX's vobra duo is ADC that targets the B7-H3 molecule
present in several tumor types 
    ** Citi says MGNX's combination therapy of vobra duo and
another experimental drug, lorigerlimab, "could unlock further
optionality in treating prostate cancer"  
    ** 9 out of 10 analysts rate the stock "buy" or higher, 1
"hold"; their median PT is $12
    ** Including session's gain, stock up 55.4% YTD

 (Reporting by Sneha  S K)
 ((Sneha.SK@thomsonreuters.com;))

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