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REG-Mural Oncology Announces Number of Relevant Securities in Issue

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WALTHAM, Mass. and DUBLIN, May 19, 2025 (GLOBE NEWSWIRE) -- In accordance with
Rule 2.12 of the Irish Takeover Panel Act 1997, the Irish Takeover Rules 2022
(the “Irish Takeover Rules”), Mural Oncology plc (Nasdaq: MURA), a
clinical-stage immuno-oncology company, (“Mural”) confirms that, as of the
close of business on May 1, 2025, the issued share capital of Mural was
17,268,881 ordinary shares with par value US$0.01 each (the “Ordinary
Shares”).  

In addition, as of the close of business on March 31, 2025, there were
outstanding 1,121,460 non-vested restricted stock units (the “Restricted
Stock Units”) and 3,725,736 options to purchase Ordinary Shares (the
“Stock Options”) granted by Mural. Upon vesting, each Restricted Stock
Unit entitles the holder to receive one Ordinary Share and each Stock Option
entitles the holder to purchase one Ordinary Share at the applicable exercise
price. 

The International Securities Identification Number for the Ordinary Shares is
IE000LK2BOB4.  

This is an announcement under Rule 2.12 of the Irish Takeover Rules.

About Mural Oncology 
Mural Oncology is a biotechnology company that was focused on using its
protein engineering platform to develop cytokine-based immunotherapies for the
treatment of cancer with the goal of delivering meaningful and clinical
benefits to people living with cancer.  Mural Oncology has its registered
office in Dublin, Ireland, and its primary facilities in Waltham, Mass. For
more information, visit Mural Oncology’s website
at www.muraloncology.com and follow us on LinkedIn
(https://www.globenewswire.com/Tracker?data=wqqOiz5EVClm4X-C4OfV3CnmmLQVmWu1fXGS1js5uMXCo9kbrMykygQQHj6pgcazjYOc_ok_8lQoOOVrzRs6HgNEuQxOlSl48AbednvknekeoYCTghe2Z0MlWe433pLprDc6a6ZXPXr2rnPmT58yobYWjIVmpSOEmz0ccyvJp8Yc5BhrD1I5cGd4sYek74W01uNYHqnFQwnmfev1nXcTWR5EgnLVzrlcP3FWHp6jJVSMnAYriPR5UXbexT4iogjL3SRPZQ2SGMMwiPao-6Kwfg==), Bluesky
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Responsibility Statement  
The Directors of Mural accept responsibility for the information contained in
this announcement. To the best of their knowledge and belief (having taken all
reasonable care to ensure such is the case), the information contained in this
announcement is in accordance with the facts and does not omit anything likely
to affect the import of such information. 

Disclosure Requirements of the Irish Takeover Rules 
Under Rule 8.3(a) of the Irish Takeover Rules, any person who is
“interested” (directly or indirectly) in 1% or more of any class of
“relevant securities” of Mural must make an “opening position
disclosure” by no later than 3.30pm (US Eastern Time) on the tenth
“business day” following the commencement of the “offer period”. An
“opening position disclosure” must contain the details specified in Rule
8.6(a) of the Irish Takeover Rules, including details of the person's
interests and short positions in any “relevant securities” of Mural.
Relevant persons who deal in any “relevant securities” of Mural prior to
the deadline for making an “opening position disclosure” must instead make
a dealing disclosure as described below. 

Under Rule 8.3(b) of the Irish Takeover Rules, any person who is, or becomes,
“interested” (directly or indirectly) in 1% or more of any class of
“relevant securities” of Mural must disclose all “dealings” in such
“relevant securities” during the “offer period”. The disclosure of a
“dealing” in “relevant securities” by a person to whom Rule 8.3(b)
applies must be made by no later than 3.30pm (US Eastern Time) on the
“business day” following the date of the relevant “dealing”. A dealing
disclosure must contain the details specified in Rule 8.6(b) of the Irish
Takeover Rules, including details of the dealing concerned and of the person's
interests and short positions in any “relevant securities” of Mural.  

All “dealings” in “relevant securities” of Mural by a bidder, or by
any party acting in concert with a bidder, must also be disclosed by no later
than 12 noon (US Eastern Time) on the “business day” following the date of
the relevant “dealing”.  

If two or more persons co-operate on the basis of an agreement, either express
or tacit, either oral or written, to acquire an “interest” in “relevant
securities” of Mural, they will be deemed to be a single person for the
purpose of Rule 8.3(a) and (b) of the Irish Takeover Rules.  

A disclosure table, giving details of the companies in whose “relevant
securities” opening position disclosures and dealing disclosures should be
made, can be found on the Irish Takeover Panel’s website at
www.irishtakeoverpanel.ie.   

“Interests in securities” arise, in summary, when a person has long
economic exposure, whether conditional or absolute, to changes in the price of
securities. In particular, a person will be treated as having an
“interest” by virtue of the ownership or control of securities, or by
virtue of any option in respect of, or derivative referenced to,
securities.  

Terms in quotation marks in this section are defined in the Irish Takeover
Rules, which can also be found on the Irish Takeover Panel's website.  

If you are in any doubt as to whether or not you are required to disclose a
“dealing” under Rule 8, please consult the Irish Takeover Panel’s
website at www.irishtakeoverpanel.ie or contact the Irish Takeover Panel on
telephone number +353 1 678 9020. 

No Offer or Solicitation 
This announcement is not intended to, and does not, constitute or form part of
any offer, invitation or the solicitation of an offer to purchase, otherwise
acquire, subscribe for, sell or otherwise dispose of, any securities or the
solicitation of any vote or approval in any jurisdiction, whether pursuant to
this announcement or otherwise.  

The distribution of this announcement in jurisdictions outside Ireland or the
United States may be restricted by law and therefore persons into whose
possession this announcement comes should inform themselves about, and
observe, such restrictions. Any failure to comply with the restrictions may
constitute a violation of the securities law of any such jurisdiction.  

Contact: 

Mural Oncology plc 

ir@muraloncology.com  

Lucid Capital Markets, LLC 

570 Lexington Ave, 40(th) Floor 

New York, NY 10022 

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