SYRE — Spyre Therapeutics Share Price
- $851.69m
- $395.03m
- 38
- 19
- 31
- 19
Growth & Value
12m Forecast Rolling | Industry | Market | |
---|---|---|---|
PE Ratio (f) | n/a | ||
PEG Ratio (f) | n/a | ||
EPS Growth (f) | n/a | ||
Dividend Yield (f) | n/a |
Valuation (ttm) | Industry | Market | |
---|---|---|---|
Price to Book Value | 2.29 | ||
Price to Tang. Book | 2.29 | ||
Price to Free Cashflow | n/a | ||
Price to Sales | n/a | ||
EV to EBITDA | n/a |
Shareholder Activity
Type | Buy / Hold / Sell |
---|---|
Institutions | |
Directors | |
Community |
Guru Screens
Quality
Name | Industry | Market | |
---|---|---|---|
Return on Capital | -37.62% | ||
Return on Equity | -91.43% | ||
Operating Margin | n/a |
Financial Summary
Year End 31st Dec | Unit | 2020 | 2021 | 2022 | 2023 | 2024 | 2025E | 2026E | CAGR / Avg |
---|---|---|---|---|---|---|---|---|---|
Total Revenue | $m | n/a | 18.74 | 2.33 | 0.89 | n/a | n/a | n/a | n/a |
Operating Profit | m | ||||||||
Net Profit | m | ||||||||
EPS Reported | |||||||||
Diluted Normalised EPS | |||||||||
EPS Growth | % | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
PE Ratio | x | ||||||||
PEG | |||||||||
Profitability | |||||||||
Operating Margin | % | ||||||||
ROA | % | ||||||||
ROCE | % | ||||||||
ROE | % | ||||||||
Cashflow | |||||||||
Op. Cashflow ps | |||||||||
Capex ps | |||||||||
Free Cashflow ps | |||||||||
Dividends | |||||||||
Dividend ps | |||||||||
Dividend Growth | % | ||||||||
Dividend Yield | % | ||||||||
Dividend Cover | x | ||||||||
Balance Sheet | |||||||||
Cash etc | m | ||||||||
Working Capital | m | ||||||||
NFA | m | ||||||||
Net Debt | m | ||||||||
Book Value | m | ||||||||
Diluted Weighted Average Shares | m | ||||||||
Book Value ps |
Other Ratios
Leverage (ttm) | Total | - Intang | + Pension |
---|---|---|---|
Gross Gearing | |||
Net Gearing | |||
Cash / Assets |
Liquidity (ttm) | |
---|---|
Curr. Ratio | |
Quick Ratio | |
Interest Cov. |
Efficiency (ttm) | |
---|---|
Asset Turnover | |
Recs Turnover | |
Stock Turnover |
Recent History
Latest interim period vs. prior period | Industry | Market | |
---|---|---|---|
Sales Growth | |||
EPS Growth |
3yr Compound Annual Growth Rate | Industry | Market | |
---|---|---|---|
Sales CAGR | |||
EPS CAGR | |||
DPS CAGR |
Profile Summary
Spyre Therapeutics, Inc. is a biotechnology company. The Company is engaged in creating inflammatory bowel disease (IBD) products by combining antibody engineering, rational therapeutic combinations and precision medicine approaches. Its pipeline includes investigational extended half-life antibodies targeting a4B7, TL1A, and IL-23. Its pipeline programs include SPY003, SPY004, SPY130, and SPY230. It has nominated development candidates for SPY001 and SPY002. Its advanced product candidate, SPY001, is a fully human monoclonal immunoglobulin G1 antibody designed to bind selectively to the a4B7 integrin being developed for the treatment of IBD. Its co-lead program, SPY002, has nominated two fully human mAb candidates designed to bind to tumor necrosis factor-like ligand 1A (TL1A), both of which are in preclinical development for the treatment of IBD. SPY003 is a discovery-stage program focused on designing antibodies to bind to Interleukin 23 (IL-23).
Directors
- Russell Cox NEC (57)
- Anthony Quinn PRE (59)
- Jonathan Alspaugh CFO (38)
- Leslie Sloan COO (50)
- Steven Weber VPR (44)
- Jim Kastenmayer GCN (49)
- Michael Hanley OTH (48)
- Hunter Smith DRC (53)
- Marcio Souza DRC (42)
- V. Bryan Lawlis IND (69)
- Alison Lawton IND (60)
- Ivana Magovcevic-Liebisch IND
- Sandesh Mahatme IND (56)
- Armen Shanafelt IND (61)
- Last Annual
- December 31st, 2024
- Last Interim
- December 31st, 2024
- Incorporated
- December 16th, 2013
- Public Since
- April 7th, 2016
- No. of Shareholders
- 26
- No. of Employees
- 65
- Sector
- Biotechnology & Medical Research
- Industry
- Healthcare
- Exchange
NASDAQ Global Select Market
- Shares in Issue
- 60,275,561

- Address
- 221 Crescent Street, Suite 105, WALTHAM, 02453
- Web
- https://spyre.com/
- Phone
- +1 6176515940
- Auditors
- PricewaterhouseCoopers LLP
Upcoming Events for SYRE
Spyre Therapeutics Inc Annual Shareholders Meeting
Spyre Therapeutics Inc Annual Shareholders Meeting
Q2 2025 Spyre Therapeutics Inc Earnings Release
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FAQ
As of Today at 23:24 UTC, shares in Spyre Therapeutics are trading at $14.13. This share price information is delayed by 15 minutes.
Shares in Spyre Therapeutics last closed at $14.13 and the price had moved by -56.48% over the past 365 days. In terms of relative price strength the Spyre Therapeutics share price has underperformed the S&P500 Index by -59.83% over the past year.
The overall consensus recommendation for Spyre Therapeutics is Strong Buy. You can view the full broker recommendation list by unlocking its StockReport.
Find out moreSpyre Therapeutics does not currently pay a dividend.
Spyre Therapeutics does not currently pay a dividend.
Spyre Therapeutics does not currently pay a dividend.
To buy shares in Spyre Therapeutics you'll need a share-dealing account with an online or offline stock broker. Once you have opened your account and transferred funds into it, you'll be able to search and select shares to buy and sell. You can use Stockopedia’s share research software to help you find the the kinds of shares that suit your investment strategy and objectives.
As of the previous close price of $14.13, shares in Spyre Therapeutics had a market capitalisation of $851.69m.
Here are the trading details for Spyre Therapeutics:
- Country of listing: United States
- Exchange: NSQ
- Ticker Symbol: SYRE
Based on an overall assessment of its quality, value and momentum Spyre Therapeutics is currently classified as a Sucker Stock. The classification is based on a composite score that examines a wide range of fundamental and technical measures. Stock are classified on the the following spectrum: Super Stocks, High Flyers, Contrarians, Turnarounds, Neutral, Value Traps, Momentum Traps, Falling Stars, and Sucker Stocks. For more information, learn about our StockRank Styles.
The analyst consensus target price for shares in Spyre Therapeutics is $54.56. That is 286.13% above the last closing price of $14.13.
Analysts covering Spyre Therapeutics currently have a consensus Earnings Per Share (EPS) forecast of -$3.45 for the next financial year.
Find out moreAn important predictor of whether a stock price will go up is its track record of momentum. Price trends tend to persist, so it's worth looking at them when it comes to a share like Spyre Therapeutics. Over the past six months, its share price has underperformed the S&P500 Index by -57.22%.
As of the last closing price of $14.13, shares in Spyre Therapeutics were trading -43.43% below their 200 day moving average. You can read more about the power of momentum in assessing share price movements on Stockopedia.
The Spyre Therapeutics PE ratio based on its reported earnings over the past 12 months is null. The shares last closed at $14.13.
The PE ratio (or price-to-earnings ratio) is the one of the most popular valuation measures used by stock market investors. It is calculated by dividing a company's price per share by its earnings per share.
The PE ratio can be seen as being expressed in years, in the sense that it shows the number of years of earnings which would be required to pay back the purchase price, ignoring inflation. So in general terms, the higher the PE, the more expensive the stock is.
Spyre Therapeutics' management team is headed by:
- Russell Cox - NEC
- Anthony Quinn - PRE
- Jonathan Alspaugh - CFO
- Leslie Sloan - COO
- Steven Weber - VPR
- Jim Kastenmayer - GCN
- Michael Hanley - OTH
- Hunter Smith - DRC
- Marcio Souza - DRC
- V. Bryan Lawlis - IND
- Alison Lawton - IND
- Ivana Magovcevic-Liebisch - IND
- Sandesh Mahatme - IND
- Armen Shanafelt - IND